6 FDA-approved medications to treat lung cancer

6 FDA-approved medications to treat lung cancer

One of the leading causes of cancer deaths, lung cancer has been known to claim more lives every year than prostate, colon, breast, and ovarian cancer together. It begins in the lungs and, depending on the stage, can spread to other parts of the body as well. Lung cancer has multiple causes. However, people who tend to smoke are at a higher risk of lung cancer. The risk increases with the length of time and the number of cigarettes smoked. Other causes include passive smoking, exposure to radon gas, exposure to asbestos and other carcinogens, and a family history of lung cancer.

Lung cancer causes coughing that doesn’t go away. Additionally, a person suffering from lung cancer can cough up blood, and experience shortness of breath, chest pain, hoarseness, unexplained weight loss, bone pain, and headache. Treatment usually includes surgery and medications. The below-mentioned medications are FDA-approved and need to be taken only when prescribed by a medical expert.

  • Xalkori: Also known as crizotinib, Xalkori has been approved by the FDA for patients with advanced non-small cell lung cancer. Earlier prescribed to those with advanced non-small cell lung cancer, this medication is now recommended to those with ROS1-positive non-small cell lung cancer that had started spreading. It works as an inhibitor in targeted therapy. It blocks the changes in lung cancer cells and that interferes with the growth and spread of the cancerous cells.
  • Tagrisso: Also called osimertinib, Tagrisso is used for the treatment of non-small cell lung cancer. The medication is a type of tyrosine kinase inhibitor (TKI); it inhibits an enzyme known as tyrosine kinases, which is involved in cell signaling. Tyrosine kinases are involved in the stimulation of cell division and are active in the uncontrolled growth of cancerous cells. Tagrisso controls these enzymes and blocks the growth and spread of cancerous cells.
  • Alecensa: This medication is used for the treatment of ALK-positive metastatic (advanced) non-small cell lung cancer (NSCLC). ALK is the anaplastic lymphoma kinase gene. In lung cancer patients, the chromosomal rearrangement of the gene causes the formation of fusion proteins in cancerous tissues. ALK then causes the uncontrolled growth of cancer cells. Also known as alectinib, Alcensa targets and interrupts ALK from stimulating the growth of cancerous cells. Additionally, it blocks the growth of the tumor and causes cancer cells to die, thus reducing the size of the tumor.
  • Gilotrif: Also known as Afatinib and Giotrif, Gilotrif is an anti-cancer medication useful for the treatment of non-small cell lung cancer. It is used for targeted treatment with better outcomes and lesser side effects. This medication works as an irreversible inhibitor of the tyrosine kinases EGRF and HER2. It slows down the progression of lung cancer.
  • Iressa: Also known as gefitinib, Iressa is prescribed for non-small cell lung cancer (NSCLC). It is generally recommended when NSCLC has spread to other parts of the body. Iressa is prescribed to those who have specific mutations in the epidermal growth factor receptor (EGFR) gene and have not undergone any previous cancer treatments. This medication works as a kinase inhibitor and blocks the proteins that aid in the growth of cancer cells. It slows down the growth of cancerous cells and reduces the size of the tumor.
  • Alimta: This lung cancer medication is specifically prescribed for non-small cell lung cancer. It is a folate analog metabolic inhibitor. Alimta is generally used in combination with platinum chemotherapy and other medications.


  • Liver Cirrhosis and its 4 Stages
    The liver is an integral organ of the human body. Therefore, the health of the liver directly affects the well-being of an individual. Liver cirrhosis is a degenerative disorder in which the healthy cells get damaged, resulting in the formation of a scar. This, in turn, leads to a reduced functional ability of the liver. A few common causes of liver cirrhosis are excess and long-term alcohol abuse, and infection due to hepatitis virus. According to a study, every year, cirrhosis is responsible for about 31,000 deaths in the country. Symptoms A few common symptoms of liver cirrhosis are
    • fatigue,
    • nausea,
    • weight loss,
    • drowsiness,
    • jaundice,
    • a loss of appetite,
    • skin problems, and
    • swelling.
    The 4 stages of liver cirrhosis There are 4 stages of liver cirrhosis, and each one of them can be differentiated on the basis of severity of the disease and complications associated with it. Two important complications associated with liver cirrhosis are varices and ascites. Varices are enlarged veins, while ascites refers to fluid-accumulation in the abdominal cavity. Both of them are an indication of portal hypertension, which is caused due to a hindrance in the blood flow through the liver. Stage 1 Cirrhosis This is the stage when neither varices nor ascites occur. However, the liver is in a damaged condition, it is not very severe. The affected individual may feel extremely tired or may experience a lack of energy to carry on regular work. Stage 2 Cirrhosis In the second stage, portal hypertension worsens and varices develop in the esophagus. However, this stage can be partially reversed if the causes are known on time and an urgent medical help is provided. Stage 3 Cirrhosis In this stage, ascites develops and varices may be present. This stage is irreversible and generally requires a liver transplant. Stage 4 Cirrhosis Among the 4 stages of liver cirrhosis, this indicates an end-stage liver disorder. In this stage, the varices of the stomach and esophagus rupture and cause intestinal bleeding, which is an immediate danger to life. A liver transplant usually the only option here. How to Deal With Liver Cirrhosis If you have been diagnosed with any of the 4 stages of liver cirrhosis, here are a few strategies that you may need to follow:
    • Avoid excess alcohol consumption
    • Take multivitamins regularly
    • Avoid nonsteroidal anti-inflammatory medication as they can worsen the situation
    • Go for a liver transplant, which is the last resort
  • How To Maintain Weber Gas Grills

    Grilling can be fun, but its maintenance surely can take a lot of time. This is something people rarely consider while buying a grilling machine. The maintenance of a grilling machine is important to ensure that the machine lasts and that you eat healthy and safe food at all times.

    How Can You Maintain Weber Gas Grills?

    Food particles often stick to the machine, leading to a poor grilling experience. The uneven heat and low temperatures can become its add-ons hindering the entire process. For this sole purpose, you need to follow certain cleaning and maintenance procedures and reduce your workload before you get down to the real job.

    • Wipe the Lid
      You should wipe the external part of the lid with a glass cleaner that is ideal for porcelain and stainless-coated products with a paper towel. Additionally, if the grilling machine is made of stainless steel, then you should use a microfiber towel to get an effective result.
    • Cleaning Burners
      For regular maintenance, you should clean the lower interior along with the burners to get rid of the grease. You can run the grill brush over the burners so that the jets are blocked. In this way, the leftover food debris and cooking grate fall into the jets.
    • Inspect Gas Hose
      You should inspect the gas hose whenever you are using the grilling machine as gas leaks are a fatal risk threat of using grilling machines. If any gas leaks occur, you can contact the manufacturer for them to take a look at the situation. Additionally, you can do the soapy water test to check whether there is any leakage any occur in future
    • Let the Residue Burn
      It is always better to leave the residue to burn, and for this, you can turn the griller to high heat for 15 minutes before you commence the grilling journey. The food particles turn into ash when the machine hits the highest temperature. This is one of the easiest ways of cleaning and brushing off the food debris that may stick to the bristle brush that is made of stainless steel.
    • Cleaning Side Tables
      If you are using gas grills from Weber, then you are generally given two side tables that you must clean using a microfiber towel. Additionally, you need to ensure that it is piled up with grain later. Mild wash detergent with warm water can be used if only your side tables are made of thermoset plastic.

    Find the Weber Gas Grills for yourself

    Weber Genesis II S-310 Gas grill

    If you are looking for a modern and posh grilling machine, you can go with this one, which is ideal for your little backyard. Running on natural gas, the product comes with three stainless steel burners and two side tables.

    • 998 square inch complete cooking area
    • 6 stainless steel burners

    Additionally, the AA battery type is good for the long haul and there is even a stainless steel lid. Designed after open cart style, the built-in lid thermometer is effective from time to time.

    Weber Genesis II E-610 Gas Grill

    Catering to every grilling need of people, this Weber gas grill takes up 770 square inches when it comes to the measurement of primary cooking area. There are six burners made of stainless steel and it runs on liquid propane. Additionally, the unbelievable features of this grill are as follows:

    • Stainless steel heat deflectors
    • Fuel gauge - LP models
    • Igrill 3 ready
    • 10 year of warranty period. This, however, excludes standard wear and tear.
    • Infinite control burner valves
    • Cast-iron cooking grate
    • The lid is completely porcelain enameled.

    If you want to look for other accessories, you can visit the official webpage of Weber to get essentials like Sear Grate and premium grill cover for the functions of the Genesis II and LX 600 Series. Additionally, for the same model, you can get a rotisserie, premium globes, and a griddle.

  • Tips to choose furniture for your home
    You have unlimited options when you decide to buy furniture. If you already have furniture at your place and are just looking to add a few more items, you need to consider certain aspects. The major concerns are price and purpose. Furniture needs space. It is essential that you know exactly why you need to buy a new set. Budget is another important aspect that must come into play when choosing your next furniture piece. Here's more. Know the purpose Consider your needs carefully. Deciding on what kind of furniture you need, where do you want to place it, and how long it is needed are essential factors to be considered. This applies to whether you already have a similar set and just want to add to it or looking for the next set for the entire home or just one room. If there is a newborn in the family, you may need a crib for the baby. You would require this piece of furniture only for a short period. When you know your needs, you can save both time and money. Plan a budget The next thing you need to consider is your budget. Knowing how much you can shell out can save you money and time. Plan your budget and stick to it. You may choose to get your furniture constructed cheaply and at the same time give it a costly look. For example, look at stores like Next Furniture. The store offers stylish designs at reasonable prices. Do not just run after the price tag; consider the quality of the furniture as well. Shortlist the store You can consider either a local furniture store or an online store to buy the furniture. Make sure you conduct a comprehensive market survey of prices, services, credit terms, and delivery services before you place the order. With online stores like Next Furniture, you can get the chance to explore various items from the comfort of your home. Do a good research If you have some basic knowledge and planning, you can buy trendy furniture and that too within your budget. Keeping your needs in mind and planning a budget before purchasing will save you lots of time and money. Compare different furniture shops for quality and design before finally purchasing the right one. These days there are new furniture materials on the market available and advanced construction techniques as well. Hence, you can go for your desired style within a set price range easily. Despite multiple options to choose from, having a sound knowledge and guidelines when buying furniture is essential. What to ask yourself before you buy? If the furniture you are planning to buy is just a quest for a statement piece, be sure about that you actually need it or not. This would help you to focus on your necessities first. If you are staying in your own house, you may go for any piece that suits your choice, requirement, and budget. If you are living on rent, you need to choose furniture that you can be moved easily. Looking for some extra furniture? A bit of planning can be helpful. Get the best value for your money next time you go out and buy furniture.
  • All you need to know about auto and homeowners insurance
    Insurance helps protect your assets in times of calamity. There are different types of insurance products available in the market that meet different needs. Two of the most important insurance products include auto and homeowner’s insurance. It is important to understand the functions and features of both auto and homeowner’s insurance. Homeowners insurance All of us put in a lot of money and effort to build our homes. In case of any unfortunate event, you may end up with a huge financial loss that you might have to incur out of your own pocket if you do not have an insurance. This is where a homeowner’s insurance comes to play. It is a property insurance which helps protect a home by providing a financial reimbursement in case of a theft or in the event of a damage. Also, a lot of home buyers in the country borrow money as a mortgage loan. In order to get the loan, the buyer must have a homeowner’s insurance. The insurance covers a loss of property, damage, or theft caused due to smoke, fire, ice, hail, lightning, and wind. It also covers natural disasters like floods, typhoons, hurricanes, earthquakes as well as acts of war. Homeowners may also purchase a supplemental insurance for an additional coverage of their property. Auto insurance Apart from home insurance, it is equally important to protect the vehicle you use. It is an asset you have purchased it at a huge cost. The insurance for an automobile is known as an auto insurance. There are different types of auto insurance policies such as a comprehensive insurance, personal injury protection insurance, liability coverage, and gap insurance. Depending on the policy you buy, it protects your automobile by providing a financial reimbursement in case of an accident or damage to the automobile due to manmade or natural reasons such as a theft or fire, respectively. The insurance will also cover third-party liabilities caused due to any damage to a third party. Therefore, if you own an automobile, it is advisable to invest in an auto insurance that meets your needs. Auto and homeowner’s insurance are two insurance products that play a crucial role in the protection of your assets. In case of any damage to the asset, to avoid incurring a huge loss for the purpose of repairs and renovation, you must buy the right insurance product.
  • Popular game consoles and their uses
    Game console refers to a gaming box containing various accessories that help gamers to connect it to the television and play games. The first game console was introduced in the 1960s. Below are few game consoles and their uses: Game console adapter: The adapters help the devices to reach the wireless networks. A short cable connects these consoles to the adapters. Certain wireless adapters are made to enable wireless gaming capacities for the comfort of the gamers. Companies like Coollead, Belkin, and Linksys provide adapters for game consoles. Game console headphones: Game consoles headphones are mainly designed to enable high definition video and audio quality experience for the gamers. This increases their interest by proving a real-time experience. The sounds of the gunshots, engine rattles, etc. are better through these headphones. Certain high-end headphones help gamers chat with other gamers in the online gaming community. Companies like Microsoft's Xbox, HyperX Cloud, and Turtle Breach provide game console headphones. Console cooling fan: Usually the consoles come with an inbuilt fan that not only cools the consoles when they are overused but also removes dust from them. However, the built-in fans wear out with use and gamers are usually recommended to use an external console cooling fan that pushes the vacuum and prevents the overheating of the consoles at the same time. However, you should check the quality of fans as low-quality fans make it hard to cool the consoles causing more harm than good. Companies like Dobe, IBSound, and Antec provide console cooling fans. Gaming drives: A true gamer will want a drive that not only enhances the gaming experience but also allows faster usage of stored information. The usual computers are not designed for this purpose, and thus gamers prefer blazing fast drives to fulfill their needs. The internal storage capacity of gaming drives is usually higher than the normal drives, and they are also reliable to handle intense desktop computing needs. However, before selecting the gaming drive, you should check if the manufacturer is reputed or not as this will question the security and reliability of the drive. Also checking the warranty will benefit you in any case of damage. A good gaming drive will have minimum two years of warranty. Companies like Toshiba, Seagate, and Western Digital provide gaming drives. A right set of game console consists of game console USB adapter, headphones, and a gaming drive that allow gamers to play on receiving the console set immediately. The price and range of accessories vary from companies and preferences of the individuals. Get all these for a great gaming experience.
  • Things to remember while buying a woman suit
    A woman’s business suit speaks volumes about her as a person. As a professional woman, you have to not only keep up your business image, you also need to portray a strong personality. A well-fitted business suit ensures that you look professional and competent at the same time. Given that these women suits last quite some time in your wardrobe, it is always advisable that you invest well into these suits and take your time in picking the right ones for your wardrobe. You cannot simply wear the same suit all year round, so you need to get a few options of women’s suits into your wardrobe, so that you have one for each distinct occasion like a business meeting with your client, an evening out with your colleagues, when you are out networking a client, etc. It is a daunting task for many women to try to find a perfect women’s suit that is perfect from color to fabric. Here are some tips that will help you pick your women’s suits wardrobe better. Don’t give up on shape. Over the ages, business suits for women have undergone a lot of fashion changes and it has gotten better with time. A good suit is considered so only if it fits you to the “T” today. You can stay on par with the current business clothing trends and pick one that is a fashion statement. But a good suit for women is beyond fad. You need to choose the right one that fits well with your body frame. Color is important. If you are picking your first women’s suit, then it is important for you to start with neutral colors so that your new clothing style does not distract people around you at work. Make sure the shoulder length of your women’s suit fits your frame and don’t go with something that does not suit your body frame. You cannot wear a puffed up shoulder design for a slanted shoulder suit. Essentially, the shoulder of your women’s suit should hug your shoulder frame and sit neatly in such a way that the fabric of your suit does not look strained or the shoulder line does not drop off your shoulder.