Multiple myeloma is a rare type of cancer that leads to accumulating cancer cells in the bone marrow. It alters the blood’s plasma cells and lowers the body’s production of disease-fighting antibodies, thus causing a wide range of symptoms in the process. However, the disease often has no signs in its early stages, making it challenging to identify. Therefore, here are the silent signs of multiple myeloma to look out for: Fatigue Healthy blood cells allow the body to fight disease and infections easily. However, with the increase of cancerous cells in the body, it has to work much harder to fight infections, causing fatigue and weakness. Bone problems Since myeloma affects the bone marrow, it can affect the process of bone cell formation, which can lead to problems like bone pain and brittle or broken bones. Kidney problems The breakdown of bone in the body leads to a rise in calcium levels, which can lead to several complications like increased thirst and urination, constipation, confusion, and kidney damage. Low blood counts The multiplication of myeloma cells in the body leads to crowding out healthy blood cells. This reduces the occurrence of red blood cells (anemia) and white blood cells (leukopenia), making one more susceptible to infections. Frequent infections Myeloma negatively impacts the occurrence of antibodies, making it challenging to fight infection-causing microbes. Numbness, tingling, or burning sensation in hands and feet Myeloma cells produce an abnormal antibody called monoclonal immunoglobulin, or the M-protein. This protein is toxic to nerves and can cause a condition known as peripheral neuropathy, which leads to numbness, tingling, or a burning sensation in the hands and feet. Hyperviscosity syndrome High levels of M-protein in the body can cause blood to thicken, giving rise to symptoms like abnormal bleeding, headaches, chest pain, decreased alertness, or shortness of breath. Conclusion Multiple myeloma is diagnosed when there is a plasma cell tumor or at least 10 percent of plasma cells in the bone marrow. It is along with the presence of one or more symptoms like high blood calcium cells, poor kidney function, anemia, tumors with holes in the bones, 60 percent or more plasma cells in the bone marrow, and increased levels of light chains. In addition, doctors may order several tests like CT scans, MRIs, bone X-rays, or lab tests to confirm the presence and spread of multiple myeloma before starting treatment.

Owning a Harley Davidson motorcycle is a great thing. Ranked among the best motorcycles in the world, every biker dreams of owning a Harley bike. The best thing about Harley motorcycles is that they can be customized to improve the looks and performance. Your Harley motorcycle is probably your most prized possession, so when there is wear and tear, you must scout for Harley parts. Custom spare parts for your prized Harley bike are not hard to find. Whether for repairing or customizing your Harley bikes, you can find spare parts online or specialized Harley stores.

Sourcing Harley parts

If you’re looking for Harley parts, look for an authorized dealer. Here, you’ll be able to find all spare parts and accessories you’ll need for your motorcycle. In addition to the current purchases, you can have a look at the product catalog and plan your future purchase of spare parts and accessories. The advantage of shopping from an authorized dealer is that you’re assured of quality. You’ll be paying for genuine spare Harley parts. Buying online is another source. You can search for websites that stock and sell Harley parts. Authorised dealer websites can also be scoured online to look for spare parts. The best websites will maintain an online catalog, allowing you to choose spare parts that suit your bike model. Verify seller background and choose to buy from sellers on the basis of positive customer feedback. If you’re looking for cheap spare parts, the best way is to source from auction sites. You can get the best bargains. On auction sites, you can find both new as well as used Harley parts. You can search for spare parts by specifying the model. In addition to the above, you can find independent sellers of Harley parts online. You can look for these sellers in your local classifieds. With so many available sources, you will surely be able to find model-specific spare parts and accessories. A cheaper option would be to buy used Harley parts. Brand new spare parts can be heavy on your pocket. Instead, you can choose to buy used spare parts and, thereby, save quite a good amount of money.

Checklist when buying used Harley parts

-Look for warranty. Although used, some spare parts will be relatively new and still covered under warranty. Ask the seller about the extent of warranty. -Shipping expenses can add up to the cost. Although used Harley parts come cheap, the shipping and handling expenses can push up the costs. When you’re opting to buy the spare parts online, be aware of how much would be the shipping expenses. -When placing an order for Harley parts online, check the duration of shipping. If the source is local, you’ll receive the spare parts soon. However, if it’s international shipping, the duration can vary from a week to a month, depending on seller’s location and the shipping agent. -Double check the returns policy. While online sales are reliable, at times, you might not get the Harley parts specified by you or they could be defective. To make sure that you don’t lose out on the refund, verify the returns policy beforehand.

Follow the latest trend

If you’re enthusiastic about trying out various accessories for your Harley motorcycle, swapping is the new trend. As a member of a Harley rider club, you can swap spare parts with fellow riders. The best part about swapping is you can personally examine and assess the Harley parts. Working like a barter system, riders exchange spare parts as per their requirements. If you don’t want to spend cash on spare parts purchases for your bike, swapping is a good option. Maintaining a Harley bike is an expensive affair indeed. However, for those die-hard bikers who swear by the power and performance of Harley Davidson motorcycles, buying new or used spare parts online and swapping help to keep their maintenance expenses low.

Heartburn is getting increasingly common in everyone’s daily lives. Though it is a problem that people tend to brush off as a minor inconvenience, it can have serious repercussions to a person's overall health. It is pointless to suffer in silence when heartburn treatment is easy to implement, as long as you know the remedy. Read on to know how effective heartburn treatment can be done at home.

• Maintain a proper posture: Do not lie down immediately after having a meal. Take a walk or indulge in household chores as this not only keeps one active but also prevents acid reflux. This helps to curb the heartburn one may expereince at night.
• Change in sleeping posture: Change the posture in which you sleep. Those who are more susceptible to heartburn during the night would benefit from sleeping on their side, the left side to be precise. Studies show that sleeping on the left side mitigates heartburn problems and also prevents them.
• Use of aloe vera: Aloe vera causes inflammation of the stomach (as well as the esophagus) to subside. It is ideally advised to have half a cup of aloe vera juice prior to a meal. However, do exercise caution while consuming it as aloe vera is known to be a laxative and excess of it may adversely affect you.
• Use of baking soda: A popular home remedy for heartburn treatment is the use of sodium bicarbonate, or baking soda, as we know it. Due to its alkaline nature, it helps to neutralize the acid in the stomach.
• Regular chewing of gum: Other than freeing the person from grips of halitosis (bad breath) and exercising the jaw muscles, chewing gum has other benefits too. For starters, it promotes the flow of saliva. Acid gathered in the stomach is washed away effectively. This is one of the preliminary yet important heartburn treatment measures.

If you are planning to pursue your MBA degree soon, it is no doubt that you are already working on ways to get yourself to the best MBA college. However, making earning your seat at the best MBA colleges takes something more than just regular. Aspiring MBA applicants bring to the table several similarities that they share with other students. Colleges review several thousands of applications that are dumped to their desk, so how do you stand out and make the final cut? Here are the traits that you should possess that will help you pave your way through competition: Successful leadership record - The most important quality that the best MBA colleges seek in applicants is a leadership quality. They are looking to develop strong leaders who can successfully contribute to the corporate landscape. As an applicant, one must be able to show admission authorities how they have successfully led co-worker or other employees in the past. Present the authorities with the times that you motivated others to carry out an action or came up with a fresh idea to bring about a change. The best MBA colleges look for students who aim to make an impact. Excellent communication skills - No matter how well your records are on paper, the ultimate trait that the best MBA colleges seek is communication skills. This is a soft skill that colleges believe to be inbuilt in a student and is necessary. A strong vision - The best MBA colleges do not want students on board who are merely looking to make their profile look fancy. They are looking for individuals who think big and aim to bring about a difference in the business world. Solution-oriented - As a business professional, one is expected to be able to think, make decisions, and execute. All that matters is the ultimate result and the best MBA colleges look for this ability and evidence that you formulated and execute an effective plan in the past.

These days, people prefer to pay by card than cash. It's safer and requires less hassle. For example, you can pay for your stay at a hotel with your credit, debit, or travel currency card, instead of counting notes in front of the hotel staff, and when strangers see the money you have, you can get stuck in the danger of robbery. Here are five best alternatives to cash that you can take along on your next overseas trip. ATM/Debit Cards Unless you overdraw your account, a debit card withdrawal won't charge you for doing so in a foreign country. However, with every payment made from ATM or debit card, you'll be charged a currency conversion fee. In addition, you will have to pay a small overseas payment fee for every payment made using your debit card. Credit Cards You can use a credit card almost anywhere for purchase and withdrawal purposes. Most hotels and restaurants throughout the world accept credit card payments, making it easy for you to pay for your food and stay while traveling overseas. To save interest, some providers offer customers to pre-load accounts with the money required during the trip. Also, for some, their savings for travel can go low; so it might suit them to pay with a credit card, pay the interest and clear the entire amount later. For those, who need not worry about breaking the bank for their travels, can skip this one. Dynamic Currency Conversion (DCC) DCC or Dynamic Currency Conversion allows a hotel, shop or restaurant to charge you in the local currency with your card. This way, you might be charged some additional fees for the service, but it's better than carrying a big fat bundle of cash, right? Alternatively, you can use your MasterCard or Visa card for making payment overseas. Many international banks offer the travel money service. So check with your bank before landing on the location, as this can save both effort and time. Prepaid Travel Currency Cards Offered by several banks and money exchange companies, travel money cards give you numerous advantages over carrying cash while traveling overseas. While loading money into the card, you have the option to lock in the exchange rate. You can use the card both for withdrawing money from ATMs and for direct payments. Unlike debit and credit cards, you do not have to pay a yearly charge. Some of the fees that you need to pay using a travel currency card are ATM withdrawal fees, exchange rate conversion fees, loading fees, and reloading fees. Traveler's Checks Some people still use the old-fashioned way of going cashless while traveling. Ever since the emergence of credit and debit cards, the popularity of travelers' checks had subsided greatly. However, there are some benefits of carrying this old-fashioned payment method. In the case of a theft or misplacement, the provider can replace travelers' checks and some foreign exchange providers even refund an unused check at no extra cost.

Sinuses are highly vascular chambers that the breathed in air travels on its way to the lungs. It functions as a sentinel to the respiratory system. There two sinuses on either side of the nose – the maxillary sinuses, two in the temporal bone just above the eye brows close to the root of the nose and two inside in front of the base of the cranium. The walls of these chambers are ridged to increase the area of contact. The incoming air is humidified, warmed, and cleansed of all particulates and bacteria, viruses and allergens. When bacteria, viruses or allergens are encountered in numbers, then blood which is equipped with large numbers of leucocytes or white corpuscles rushes in to destroy these aliens. It is this that causes the congestion. The best thing to counter the congestion to is to help the body fight its war by taking rest so that all its energies are deployed at the war front and eat nutritious food. Stuffing a cold is an age-old ‘grandma’s’ prescription. Drinking a lot of fluids helps to keep one hydrated and this is also a useful sinus congestion relief. Old grandma’s chicken soup is also highly recommended. Herbal teas such as ginger tea or mint tea also are effective for sinus congestion relief. These herbs have anti inflammatory properties. These are very useful for sinus treatment. Steam inhalation is another time-tested sinus treatment remedy. There are special kettles called inhalers, and these are safe. Of course, one can boil water in a wide mouthed vessel and place the face a safe way up and cover with a tent made of a thick towel and breathe the steam in deep. One can put a few grains of menthol, camphor or a few drops of eucalyptus oil. These are good vasoconstrictors and help reduce the congestion. If the congestion persists for more than the current ten days or the symptoms worsen or the nasal discharge turns yellow, it is time to call a doctor. The most important things to take as much rest one can and consume protein rich food.