5 natural ways to keep your nails healthy If you ignore your nails, you may end up having an issue or two. The first thing that you might want to do is to start taking care of your nails and use kitchen-based ingredients that might solve the nail problem. Poor diet, lack of hygiene, etc. can cause nail issues in both men and women. When you see yellow, brittle nails or nails with lines or dents, you know there’s an issue. Try these kitchen ingredients to treat them. Apple cider vinegar With a high concentration of malic acid and acetic acid, apple cider vinegar can reduce discoloration of the nails. Moreover, it has anti-fungal properties which can treat numerous infections of the nails. It is also proven to help in stimulating and strengthening the growth of nails. Orange peel Orange contains copious amounts of vitamin C which can assist in warding off the yellow stains. Simply rub orange peel twice or thrice in a day to earn desired results within a week. You may also make a paste of orange peel and apply the mixture on the nails and keep them for about 10 to 15 minutes. Remove it gently with the help of a soft toothbrush and wash it with lukewarm water. Baking soda This kitchen ingredient has exfoliating and bleaching properties that can aid in eliminating the stains out of the nails. Mix up baking soda with 3 percent hydrogen peroxide in a bowl and then apply this mixture to your nails using cotton swabs. Finally, rinse off the nails with warm water to see desired results. Lemon Lemon helps in warding off the yellow patches on the nails and helps to lighten the skin around the nails. It can also act as an astringent for your nails and prevents the nails from infection. Garlic This does wonder for your nails. Crush some raw garlic and apply on your nails or add it to a small tub of water, and soak your feet in it. The antibacterial properties of garlic will remove the fungus effectively. Conclusion With these few kitchen ingredients, you maintain healthy nails that look and feel good. But if it doesn’t give desired results, you should see a doctor to see if you have any underlying health complications.

There are mints all over the world that create and distribute silver bars. Several mints that create silver bars are A-Mark, Asahi, Atlantis mint, Geiger, Engelhard, Highland Mint, Johnson Matthey and Silvertowne. But Engelhard is perhaps the most well-known minter of them all. They have been in business for over twenty years and are recognized as the most renowned brands in the entire bullion industry. The desire and the demand to buy silver bars from Engelhard brand is so high that the value of these bars is even higher than the value of silver coins. A-Mark is a metal trading company located in Santa Monica, California. They started small but have grown to be one of America’s largest distributors of gold, silver, and platinum. The 10oz A-Mark silver bar is the most popular product of this company. Asahi is one the newest companies to enter into the precious metals industry. They have quickly moved to meet distributor’s demands of gold and silver bars. Asahi Refining facilities first started with the production of the 100oz silver bars featuring a rustic and simple design. Each silver bar is stamped weight, purity and assayer’s mark of the brand. Geiger Edelmetalle is the producer of the popular security line of silver bars. This is an esteemed German mint that has made a mark on the US precious metal industry. The unique part about this mint is that they offer as small as 1 gram to a huge 100oz bar with a wide variety of sizes in between to people who want to buy silver bars The Highland mint although widely known for minting official sports coins and medallions, they do make silver bullion products for distributors. There a wide range of silver bars made by the company and they ensure uniqueness with all their products. Their state of art facility is located in Melbourne, Florida. The 10oz horse silver bars featuring galloping horses are trendy. Silver bars are made in many other mines as well and it makes for wise decision to buy silver bars for investment purposes.

Bladder cancer is considered as the most common types of cancer and is likely to affect men more than women. Recently, the Food and Drug Administration (FDA) approved the use of Nivolumab for the treatment of patients who have bladder cancer. The combination of Nivolumab and Ipilimumab was evaluated in an appearance I clinical trial. In a recent research, 41 patients were treated with a Nivolumab 1mg/kg plus Ipilimumab 3mg/kg dose, out of which doctors got few positive and good results. Nivolumab is used for the treatment of metastatic bladder cancer among patients whose disease has gotten worse. The FDA approval given to use Nivolumab for the treatment of metastatic bladder cancer was on the basis of the results of Nivolumab clinical trial, which gave positive results. Nivolumab clinical trial was done on 270 patients who were suffering from advanced or metastatic bladder cancer that had worsened over time. 19% of these patients who received Nivolumab had tumor shrinkage for a median of 10.3 months. Out of 53 patients who had tumor shrinkage, 7 patients had complete tumor shrinkage and 46 patients who had partial tumor shrinkage. Nivolumab functions by releasing a protein called Pd-1 on cancer-fighting immune cells called T cells. Once Nivolumab releases PD-1 protein, T cells can destroy the cancer cells. Implications of Nivolumab As there were few options available for treatment of metastatic bladder cancer, doctors started using Nivolumab soon after Nivolumab clinical trial results were approved by FDA. In contrast to typical short-lived responses with cancer therapy in solid metastatic tumors, many responses induced by Nivolumab appear persistent. These persistent results only increased the use of Nivolumab for people who have metastatic bladder cancer. Note of caution If a patient is or was on some prescribed drug or has used some herbal products, then he/she must tell this to the doctor before using Nivolumab. Although Nivolumab clinical trial results are positive and FDA-approved, there are many drugs and over-the-counter medicines, which can interact with Nivolumab and deteriorate the situation.

Gaming station or consoles are absolute necessities for a large number of gamers. However, they're costly. In any case, one can get old consoles and amusements at significantly less expensive costs, and look at the best diversions arrangements to ensure one is getting the best cost. Thus, analyzing the pros and cons of the different gaming consoles available in the market for kids as well as adults, and choosing which one will suit your requirements is quite a demanding and challenging task. Gaming station for adults vs. gaming station for kids Well, the most haunting question for any gamer would be what will be the best gaming system for adults and the best game console for kids. Would it be Xbox One or PS4? Or, then again perhaps one should go for a handheld console like Nintendo Switch. If children are at the age where one is thinking about purchasing a gaming support, now may be the opportune time. New improvements, including the acquaintance of virtual reality, recreations offer more authenticity, intelligence, and adaptability than any time in recent memory. The best gaming console for kids Just in the case, where children are enthusiastic about recreations, these machines are the best while going for consoles. Remember that, however, there are a lot of amusements for each support intended for the tweens and more youthful, by far most of PlayStation 4 and Xbox One diversions are exceptional and developed to perfection for being selected as the best game console for kids. Sony has the edge for genuine gamer families with its PlayStation headset intended to work with the PS series. PSVR gives an immersive, virtual reality amusement encounter. Xbox One is a superior decision for families who officially possess a great deal of Xbox recreations, as the Xbox will play some Xbox 360 games. Likewise, every unit has its own importance to be selected as the best game console for kids. The best gaming system for adults It's an interesting time to purchase the best gaming systems for adults. Three years into the present support age, we see another variety of incrementally enhanced equipment. This is to some degree hazardous, as the essential advantage of a gaming console is its effortlessness. There are many convincing contentions in the matter of why players who think about execution or need access to the best number of recreations ought to put resources into a gaming PC. There are a couple of recreations for each of the best gaming system for adults that take the full favorable position of these highlights, we as of now don't prescribe that you purchase another TV for high-determination gaming.

Selecting a wireless phone plan earlier was forthright. Choose the number of minutes you needed and then sign a 2-year agreement. But, you now have a plethora of lease plans, installment options, shared data, and BYOD plans to choose from. Service providers have made it quite difficult to find the final prices for the best android phone plans they offer. Handset charges, lower rates for contracts, outright buying discounts, unlimited data options can make this simple task confusing. In most cases, the rates you see advertised and what you pay at checkout will not be the same. If that’s not enough, then you must consider network speed, coverage area, and additional benefits you get with the smartphone. Here’s what you can do to save money on your phone plan: Old style 2-year agreements: Getting new plans with a traditional 2-year contract are very few and far right now. T-Mobile was the first eliminate 2-year contracts followed by Sprint, AT & T, and Verizon. Only existing customers can avail this plan, while new consumers do not get this option. Quick-upgrade plans: Sprint, AT&T, and T-Mobile now have plans that let you pay the charges in installments for a discount in exchange. Moreover, you can get a new phone every year or so, if you return the device to the provider. On the other hand. if you opt for such a plan, you manage to save significantly as compared to the traditional 2-year contracts. No contract, an installment plan only: T-Mobile has eliminated contracts completely and now offers a strictly financed phone model. You pay the full retail price in installments instead of paying access charges on your bill. Pre-pay virtual carriers: Regional carriers like Cricket Wireless, Boost Mobile, can help you save a lot every month if you are fine with their limited phone options. Most regional providers are supported by the major players, so you get the same speed and coverage at substantial discounts. But the biggest cons are very limited phone selection and high initial handset rates.

In type 1 diabetes, a person's pancreas fails to yield the required insulin in the body. This naturally leads to an increased amount of glucose in the blood, which can be quite damaging in the long run. To understand how type 1 diabetes works, one must know its causes and symptoms well. Causes of type 1 diabetes Type 1 is often caused by an autoimmune disorder that misunderstands the body's mechanism, and attacks the beta cells in the pancreas that are responsible for producing insulin. This results to negligible or zero production of insulin. It still isn't entirely clear what leads the immune system to behave erratically. The two main reasons for the malfunction in the immune system are: Genetic coding “ People with a certain type of susceptibility gene are prone to develop type 1 diabetes. Therefore, some ethnic populations are more likely to suffer from type 1 diabetes. Viruses “ A person who has recently suffered from a viral infection might be vulnerable to type 1 diabetes. This is because the body starts to produce antibodies to destroy the invasive viruses. Although not every virus is responsible for this condition. Watch out for viruses like Rotavirus, coxsackievirus, rubella, mumps, cytomegalovirus, and Epstein Barr, as they are closely linked with the onset of type 1 diabetes. Several studies are still attempting to dig deeper in order to conclude other possible reasons for the generation of type 1 diabetes. Symptoms of type 1 diabetes Fatigue “ If you are feeling unusually tired/weak all the time, immediately start paying attention to your body for other possible symptoms. Exhaustion is often one of the biggest signs of diabetes. Frequent urination and excessive thirst “ Urinating often is a way through which the body eliminates the excessive sugar. This condition is generally observed during the nighttime. Urinating excessively naturally leads to excessive thirst, as you require water to keep the body dehydrated. Blurred vision “ Increased sugar can cause the lenses in the eyes to swell. This causes eye dryness and eventually leads to blurring of the vision. Weight Loss “ Unexplained weigh loss occurs in a diabetic condition because the inadequate insulin cannot use the glucose for generating energy. Therefore, the body then seeks the assistance of the existing fat for energy. Loss of appetite, stomach cramps, vomiting, and skin infections are some other serious symptoms of type 1 diabetes.