Metastatic cancer is a tumor which spreads from an initial site to different locations within the body. Cancer cells can spread to closer lymph nodes, tissues, and organs. This is how metastatic cancer occurs and it generally happens at stage IV of cancer. Metastatic cancer is identified by the primary cancer name. For example, breast cancer that has been spread to the lungs is called metastatic breast cancer. The cancer cells in the lungs will have the same features as that of breast cancer. How it spreads The disease is dangerous because of its ability to spread to different parts of the body. The cancer cell multiplies at the primary location and invades nearby tissues and moves through blood vessels or lymph nodes to the other parts. The most common parts where cancer is spread are the lungs, liver, and brain. Breast cancer is spread to the bone, brain, liver, or lung where it reflects the metastasis breast cancer signs. Sign and symptoms of metastatic cancer There are no early signs of metastatic cancer. However, when they do appear, they depend on the location of the tumor. Some of the most common symptoms that are related to the lungs, liver, brain, and bones are:

• Lungs – Individuals experience a chronic cough and breathlessness.
• Liver – Affected people may experience nausea, jaundice, and the possibility of an enlarged liver. This condition may also cause itchy skin, abdominal pain, or a loss of appetite.
• Bones – When it affects the bones, people experience severe pain and swelling in the bones and joints. Also, the bones may be susceptible to fractures.
• Brain – When cancer metastases to the brain, neurological disorders such as severe headaches, seizures, or vertigo may be considered as some of the symptoms. Individuals may also experience vision disturbance, nausea, or behavioral changes.

Metastasis breast cancer occurs after several years of primary cancer and may be diagnosed at the initial stage. There are no major metastatic breast cancer signs. Some common symptoms include:

• Severe pain in the breast and discharge from nipples
• One of the most common metastasis breast cancer signs is a lump or thickening on the breast and near the underarm
• It may cause pain in the bones and the bones may be vulnerable to fractures

The treatment is determined by whether the cancer is localized or metastasized. If cancer has metastasized, it increases the probability of a patient’s death. There are malignant cancers that kill persons with metastasis. Metastasized cancer can be treated with chemotherapy, radiation therapy, biological therapy, hormone therapy, surgery, or a combination of these.

Cushing syndrome is a disease which occurs when the patient's body has been exposed to extremely high levels of the hormone cortisol for a sustainable and long period of time. Cushing syndrome, which in medical parlance is called hypercortisolism, may be caused by the use of oral corticosteroid medication among many other things. An excess of cortisol is capable of producing some of the most typical Cushing disease symptoms, which include a possible fatty hump between the patient's shoulders, a rounded and wholesome face, and pink or purple stretch marks on the skin. The various signs and symptoms of the Cushing syndrome are known to vary from person to person depending on the levels of excess cortisol in the concerned patient's body. Common signs and symptoms of Cushing syndrome The most common Cushing disease symptoms involve progressive obesity and skin changes, such as:

• An immense amount of weight gain as well as a deposit of fatty tissue, particularly around the middle section of the body and upper back. Other common areas of the body where it happens are the face, where it is called the moon face, and sometimes between the shoulders, commonly known as the buffalo hump.
• Colored patches like the pink or purple stretch marks, known as striae, on various parts of the skin like the abdomen, the thighs, breasts, and arms as well.
• Thinning of the skin accompanied by immensely fragile skin that bruises easily and stays bruised.
• The cuts on the patient's body take an immense amount of time to heal, as do insect bites and infections and all other kinds of skin problems.
• Patients suffer from acne.

Cushing syndrome symptoms in women Women may experience some of the following Cushing disease symptoms:

• Their body and facial hair may grow thicker and consequently become more visible.
• Their menstrual periods may be impacted in terms of regularity and uniformity.

Cushing syndrome symptoms in males Men who suffer from this disease may experience the following Cushing disease symptoms:

• A great deal of fatigue.
• Weakness in their major muscle groups and a general weakness.
• Mental repercussions may include depression, irritability or anxiety.
• The dysfunction of their sexual organ and a decreased efficiency at sex.

In conclusion, it might be said that this disease should not be neglected under any circumstance, and if a patient is experiencing any of the above-listed symptoms, they should visit the doctor.

Atopic dermatitis, otherwise referred to as eczema, is a skin condition characterized by inflamed, red, rough and blistered patches of skin. There are two primary causes for the onset of eczema. They can be hereditary or environmental factors. The environmental factors that can contribute to eczema includes irritants including soaps, shampoo, conditioners, etc., microbes such as bacteria,extreme temperatures such as high temperatures and high humidity. Hormonal changes, especially in women during their menstrual cycles or during pregnancy can also lead to eczema. Having any one of the symptoms doesn't necessarily mean that you have eczema. If you have two or more of the symptoms, consult a dermatologist immediately. Early detection of eczema is the key to effective treatment. If your skin is constantly dry and sensitive, it may be a symptom of eczema. Unstable behavior of a skin with frequent rashes due to temperature change should be monitored. Intense itching sensation, dark colored patches, swelling etc are all common symptoms of eczema skin. In case you have eczema, consult an allergist. They run several tests to confirm the skin condition. Allergists may use these 3 methods to confirm their diagnosis.

• Patch testing Substances are carefully placed on the surface of your skin to see how your skin reacts to them. This test determines what skin allergy you might be having.
• Skin prick testing A needle containing a little amount of allergen (a substance that causes allergies) is injected into your skin.
• Food challenges Certain food items are eliminated and introduced into your diet. This helps determine if it is a food allergy.

There is no actual cure or formula to cure eczema. However, there are ways you can heal your skin and prevent flaring of the symptoms. Being committed to change your lifestyle will increase your chances of becoming eczema free. Check out some of the ways listed below that can help you mitigate and prevent eczema.

• Set aside regular intervals during the day when you can take warm baths.
• Use a mild soap on consultation from your dermatologist.
• Use a towel to pat the surface of your skin rather than rubbing.
• Avoid activities that cause excessive sweating. Sweat acts a catalyst for eczema.
• Use a humidifier if you are staying in cold or dry climates.
• It is always safer to prevent the disease than fight it.
• Use cosmetic with fewer chemicals. It is safer to use fragrance-free, bland moisturizers which contain fewer chemicals. Cosmetics, in general, may have agents that could harm your skin.
• Choose your detergent wisely. The modern liquid detergents or even the fabric softeners make your clothes softer. However, they might stimulate itches. As a general thumb rule, simply avoid anything that creates an itching sensation.
• Avoid bathing in lukewarm water as it causes your skin to dry up slower than in hot water.

Higher uric acid levels can cause serious health problems. It can result in gout arthritis, kidney stones, and even renal failure. Recent studies have shown other complications associated with it. A higher uric acid level may lead to hypertension and cardiovascular diseases as well. Causes of high level of uric acid in the body An increase in the level of uric acid in the blood happens because of an increase in the production of uric acid. Another reason is slow excretion of uric crystals from the kidney. The causes of this health condition are:

• High-purine diet including foods like red meat, seafood, and pulses
• Excessive intake of alcohol
• High consumption of sugary foods
• Existing renal problems
• Obesity
• Less active thyroid
• Low immunity
• Genetics

Prevention is the cure If your initial diagnosis shows higher uric acid level, you can control it. You can follow these simple steps to avoid a health disaster.

• Avoid a high purine diet to exercise control over uric acid levels
• Avoid high fructose food products
• Drink alcohol in moderation
• Reduce your weight
• Drink lots of water

All these would ensure that your uric acid levels stay in control. Following a strict diet can help lower uric acid levels. Here's what all you should eat. Diet to follow

• Cherries and strawberries as they have anti-inflammatory properties
• Lemon juice, as the citric acid in it neutralizes uric acid
• Apple cider vinegar flushes uric acid out of the body
• Baking soda makes uric acid more soluble and flushes it out of the body
• Olives and olive oil lowers uric acid content in the body
• Eat organic eggs as they contain less purine
• Flaxseeds reduces uric acid level and inflammation in joints
• Vegetable juices like carrot and cucumber juice keep the body hydrated
• Green tea lowers uric acid

Besides making changes in your diet, it is important to exercise to maintain a healthy weight. Regular exercising helps in dealing with weight management issues. It is also helpful to keep your uric acid level in check. Symptom management The initial signs of excessive uric acid in your body includes:

• Inflammation and redness in the joints
• Excessive pain in the joints
• Swelling at the base of the big toe
• Tenderness of joints
• Swelling or redness of ankles, knees, fingers, elbows, and wrists
• Lumps beneath the skin
• Kidney stones

You need to undergo a simple blood test to know uric acid levels in your body. It is good to get a routine test to avoid a serious health disorder later. A high uric acid level is not too harmful and is controllable too. But if the uric acid is excess in the blood, then you are likely to experience serious gout or kidney problems.

Nokia has been seen as a game changer, ever since it came into the market. Some swoon over it, some dismiss it as a fad but no matter what you do Nokia is here to stay and how. With the search for the new Nokia 105 on among buyers, one question that might puzzle you over time is how safe is it to buy a Nokia 105 from a reseller? If you doubt that the reseller does not give you genuine quality, you can bid goodbye to those doubts. Well, you can find the right refurbisher or a reseller if you know how to look right. To begin with, you will have to understand how official or how reputed the reseller is. A lot of them have arrived and mushroomed around your area but then there are certain resellers who have been in the business for a long time, and these are the names that can be trusted to give you a Nokia 105. A for Authenticity Make sure your reseller has all the papers in place. This is because there are resellers who would give you great discounts on the Nokia 105 but the phone could come without any original documents. This poses to be a risk when you go ahead to claim some repair services later on or even to check the authenticity of the phone. For a genuine Nokia 105, you need to look around in the real marketplace. Go for sellers who have good word of mouth reputation. It is easy to bank on one who has already sold something to a friend or acquaintance of yours. Additionally, when you find a Nokia 105, make sure that it is not a copy product since the Southeast Asian market has given rise to a lot of copy products infiltrating the local market. You will have to look for the real logos and the authentic IEMI number to verify the making origin of your Nokia 105. Go Online Additionally, look for online resellers or official resellers but ensure that their websites are secure. There are a lot of online retailers who have also started reselling Nokia 105s in tie-up with the manufacturers. Do some groundwork, rummage the Internet and make sure you pick the resources that could give you access to the best and most affordable deals. Nokia phones are a rage that will not die down anytime soon. It is always okay to go in for an option that suits both your needs as well as your wallet. Once you make your mind up about buying a Nokia 105 model, there are a lot of options to bag excellent reseller deals.

The Apple event on the 12^th September 2018 at California saw the release of three most-awaited smartphones of the year the iPhone XS, iPhone XS Max, and iPhone XR. With this year's launch, Apple has remained loyal to its design elements just a few tweaks here and there to keep the iPhone XS a standout from its predecessor. If you're someone who prefers superior-quality phone features packed with a vast storage capacity, then the iPhone XS 256GB is the phone for you! Display Super Retina and custom OLED take things a notch higher An all-screen design offers you a larger canvas. The 5.8-inch Super Retina custom OLED display coupled with 2436x1125 resolution and 458 pixels per match make the iPhone XS 256GB perfect for those who love to watch movies or play games on a larger screen not to forget, the vast storage capacity. The custom-built OLED brings an HDR display backed with the industry's best-in-class color accuracy, true blacks, and outstanding brightness and contrast. Apart from these two excellent features, the iPhone XS 256GB comes with HDR10, wider stereo sound, and True Tone display. Intelligent A12 Bionic chip If you thought A11 chip was smart, then you're yet to experience the best in the smartphone industry A12 Bionic chip. The iPhone XS 256GB is powered by the ultra-smart A12 Bionic chip coupled with the ingenious Neural Engine, offering a top-notch experience in photos, videos, gaming, and overall augmented reality. It uses the next-gen machine learning technology delivering powerful performance and user experience. The two performance cores are designed to manage tasks that demand heavy computing, whereas the four efficiency cores handle everyday tasks efficiently. Apart from the immaculate capabilities, the A12 Bionic chip is designed with intelligence saving enough battery life for other tasks. Impeccable camera features Nothing beats a great camera phone and Apple iPhone XS 256GB has exactly the right blend of camera features that one can think of. By harnessing multiple technologies, such as an enhanced ISP, faster sensors, and cutting-edge algorithms, the smart HDR helps bring better highlights and clearer shadow details to the photos. The iPhone XS 256GB features a 12MP dual wide-angle and telephoto cameras along with the Dual OIS for sharper and smoother 4K videos. Moreover, the 7MP TrueDepth camera offers enhanced portrait mode selfies. Advanced Face ID for impeccable security What's more secure than unlocking your phone using your face as the password? The iPhone XS boasts an advanced Face ID that can help unlock the apps, log in to apps, and pay for various purchases all with your Face. With the most secure and faster facial authentication in the industry, you're sure to experience advanced yet easy-to-use security. Different color and price variants The Apple iPhone XS is launched in three color variants Gold, Space Gray, and Silver, whereas the storage capacity variants include the iPhone XS 64GB, iPhone XS 256GB, and iPhone XS 512GB. The three latest Apple smartphones are priced at $999, $1,149, and $1,349, respectively.