Cancer is a disease that can’t be treated without proper diagnosis and medical care. Cancer cells cause enormous damage to the body, which is irreversible. Recurrent multiple myeloma is a phenomenon when cancer returns after a period of remission. Multiple myeloma doesn’t have any cure, and it is true that patients will certainly relapse at some point; this is why recurrent myeloma is also known as relapsed multiple myeloma (RMM). Scope of Treatment for Relapsed Multiple Myeloma Multiple myeloma doesn’t have any treatment; however,  decoding the DNA has enabled doctors to treat patients with relapsed myeloma. Depending upon the condition and the responsiveness of the patient, there are four ways that can be used for the treatment of RMM.

• DNA Alteration: DNA alteration treatment is used when it is considered that the patient is suffering from t (4, 14) disorder, which involves chromosome translocation. It has been clinically proven that patients with this form of RMM respond well when they are treated with a proteasome inhibitor.
• Progression Free Survival: If a patient has had a positive response to the prior treatments of cancer and the relapse has still occurred, it could be beneficial to opt for progression free survival. In this form of relapsed multiple myeloma treatment, it has been clinically demonstrated that patients with an intermediate risk respond positively if properly retreated.
• Switching Drug Class: Patients who have not reacted positively to their prior treatment of cancer may be asked to opt for the drug switching treatment. Almost 20% of high-risk patients have been better off with this treatment and when consulted with expert oncologists, the outcome can be positive.
• Cytogenetic: This is one of the newest forms of therapy for the treatment of relapsed multiple myeloma. Using this, researchers argue that patients with t (4, 14), del17p or t (14, 16) can be treated better than any other method. However, due to the lack of any evidence, there is no support for this form of treatment.

Treating RMM is certainly a challenge, but if a patient is treated with good care and all the parameters such as age, health, genomic test results are taken into consideration, it can help in curing the relapse.

Inkjet printers use inkjet technology for printing. This technology involves ionized ink being sprayed onto papers. This ink is directed towards the paper using magnetic plates. Inkjet printers were the only choice of printers till the introduction of laser color printers. However, these are still used by homes and businesses as the cost of inkjet printers are cheaper than contemporary ones. One of the best advantages of such printers is their cost. Before using an inkjet printer there are certain things you should know about them:

• Smeared and smudged ink: The print quality of pages produced from an inkjet printer is not as great as the contemporary laser color printer. The ink from these printers tends to smudge and smear if not dried properly or when it comes in contact with moisture. Smeared and smudged ink will ruin the overall appearance of your documents. This may be the case with portable inkjet printers as well.
• Slow printing: Inkjet printers are not very efficient when it comes to printing large volumes within a short time. These take longer and can only support small volumes. This is why a lot of homes and small-scale businesses opt for a laser color printer or any other kind over the traditional inkjet printers.
• Maintenance: The toner cartridges for an inkjet printer tend to dry run out fast and require regular replacement if the printer is often used. This disadvantage is inconvenient and also incurs a maintenance expense from time to time. These cartridges also require to be cleaned now and then.
• Need for a high-grade paper: As compared to other contemporary printers like the laser color printer, inkjet printers offer their best only with high-grade paper. Using paper of a lower grade can spoil the print or the paper. This only increases the cost of having an inkjet printer.

Whether you opt for a laser color printer or an inkjet one, it will depend on your usage. While it may not be ideal for your professional printing needs, it may be suitable for homes where you don't need to use the printer frequently.

A handbag forms an essential component of our everyday life. Not only do we carry all our essentials in our bag but it also serves as a great fashion accessory. Several brands offer a range of handbags to boost your style quotient besides ensuring convenience and comfort. Belk is one of the finest retailers around, which sell handbags suited to all needs and ages. If you know your needs well, it becomes easier for you to choose as you narrow down your search for a great handbag. This article provides you an insight into choosing the right one amongst the many Belk handbags, keeping your needs and style statement in mind.

Know your needs

The primary purpose of a handbag is to accommodate your essentials and provide you with ease of carrying. While buying a handbag, you should know your needs well, i.e. what you want to accommodate in the handbag and how. Size does matter when it comes to handbags. Belk handbags come in a wide variety of sizes, shapes, types, and colors. Visit Belk’s official website and check out the different styles, such as the New Directions Shoulder Bag, Bueno Studded Multi Zip Crossbody, and Nine West Maddol Tote. If you want to carry the handbag to your workplace regularly, you need to buy a spacious one which will accommodate your everyday essentials, purse, phone, and stationery. If you want a handbag for occasional use for outings or parties, you can buy a smaller one. Ensure that the handbag you buy gives you maximum convenience. The types of Belk handbags available online include totes, crossbody bags, designer bags, satchels, shoulder bags, hobo bags, mini bags, backpack purses, clutches and evening bags.

Prioritize on comfort and convenience

While buying a handbag, ensure that you choose one that you can carry around easily. Make sure that the handbag is spacious enough. You should be comfortable putting things in and taking them out with ease. Check out the Belk handbags which come with multiple compartments for you to accommodate your essentials in an organized manner. Kim Rogers Kamino Satchel and the Brahmin Melbourne Collection are perfect handbags to accommodate all your daily essentials. Choose a handbag which allows easy usage. You should not have to rummage through your entire bag in order to take out your phone. Go for Belk handbags which enable you to systematically arrange your things, thus ensuring convenience. Check out the Steve Madden Bevelyn Studded Strap Mini Bucket Hobo, which comprises of multiple compartments, enabling you to comfortably carry your belongings.

Flaunt your style quotient

Handbags serve as great accessories to your clothing. Sometimes, one’s style does not seem complete without a handbag. You can buy Belk handbags online, suited to your personality and fashion taste. There are handbags perfect for different occasions and outfits. You can choose from a multitude of colors, designs, and sizes. Belk has some stylish crossbody bags as well, such as, the Bueno Veg Tan TZ crossbody, which is a style statement in itself! While buying handbags according to your style, you should consider the kind of outfits that you have. Keep in mind the occasion for which you are going to carry the handbag. Match it with other accessories such as shoes, belts, or bracelets. You can choose from a plethora of designs, ranging from minimal to elaborate. Asymmetrical handbags are the latest “in” thing, owing to the nice oomph! factor that they add to your personality.

Look for offers, deals, and discounts

Belk handbags offer some great deals and discounts on different styles of handbags. You can check out the latest sales on the official website as well as on fashion and lifestyle blogs. Keep track of the latest discounts. Belk.com has regular discounts on many handbags almost throughout the year. While buying a handbag at a discounted price, remember that you should not be compromising on quality. Check out the specifications, structure, design, size, and color of the handbag properly before buying. While ordering online, check if you can avail some promo codes as well by referring your friends. Buy handbags suited to your budget, needs, lifestyle, and personality. Here are a few quick tips for you to keep in mind while purchasing a Belk handbag. -Pick the right size. -Do not compromise on quality. -Buy a handbag which is a good blend of style and comfort. -Assess needs and occasions. -Keep track of the latest deals, discounts, and offers on handbags. -Order online and have the handbags of your choice delivered at your doorstep.

Red Wings has been synonymous with sturdy and durable workwear boots. Made for tough jobs that require a person to stand all day and walk over wobbly and slippery surfaces, Red Wings boots have always been the choice of footwear for the rough-and-ready workmen. These workwear boots are made of leather that can weather any season (rain, snow, frost or sweltering summer heat) and working conditions: concrete floors, oil-spilled floors, unsteady surfaces, muck, water and so on. Red Wings boots for work are made with the sole intention of protecting the feet from different hazardous work environments. The boots have been designed for everyday use as well as for extreme work use. Having initially designed for heavy industrial work, Red Wings is slowly expanding towards shoes made for everyday regular use. Here are 4 Red Wings boots that are versatile as well as durable. Men's LoggerMax 9-inch Logger-Lineman Boot: These heavy-duty Red Wings boots are best for those who work in the oil and gas industry and in the forestry. These boots have aggressive and strong lug sole that provide great support to your feet and stability to your posture when you have to stand for long hours. With shanks made of steel, the outsoles are resistant to heat, gas and oil spills Men's King Toe 6-inch Boot: These light-weight Red Wings boots have a non-metallic toe. Suitable for those in the manufacturing industry and commercial construction industry, these boots are slip resistant and protects the wearer from spills as well as electrical hazards. The fronts of these boots are quite roomy; this makes them perfect for those who have foot problems such as hammer toes. Men's DynaForce 6-inch Boot: These Red Wings boots have been made for people who work as trade contractors, mechanics, outdoor workers people who work long hours standing on hard surfaces. These boots are resistant to oil, chemical, heat and abrasion. With the shanks made of fiberglass, these boots provide good protection and support to your feet with steel toes. The boots' outsole has welt constriction that provides good stability to your feet. Men's SuperSole 2.0 8-inch Boot: Made of Nutmeg Ebbtide leather, the SuperSole insulated well against electrical hazards and is water-proof as well. Its outer sole is puncture-resistant and protects against chemical as well as an oil spill. These all-weather Red Wings boots are suitable for winter as well as for the rains. Although it is hardy on the exterior, its inner sole is soft enough to provide comfort and give cushion support.

When you bought a water filter you might not be aware of the type of system that had been installed in your house. It is possible that if you were aware of the functioning, you might not have bought that particular type of water filter. There are different types of water filtration systems that are made to serve different purposes. Read along for details on four different types of water filtration systems and their functions. Activated carbon filters The activated carbon filters are also known as carbon filters or pre-filters. Their job is to get rid of the large particles in the water, such as sediment and silt. The activated carbon works in attracting the harmful particles and eliminating them from the water that leaves the faucet. It also removes the odor from the water and makes it taste significantly better than ordinary tap water. Reverse osmosis This is one of the most popular forms of filtration when we talk about water filtration. This is mainly because it has the potential to eliminate all the contaminants that can harm the human body. The end result after the water filtration is clear and odorless drinking water. Alkaline or water Ionizers The alkaline process of water filtration is known as electrolysis. In this process, the water passes over electrically charged plates that separate it from the contamination. Once this is done, the water is separated into two streams which are alkaline and acidic. This process converts hard water into soft water as well as filters away the acidic content, which makes it better for your skin. UV filters This is one of the latest ways of filtering water but it is not as effective as the other methods mentioned above. The solar energy has the potential to destroy most of the contaminants, however, there are some that get away. These contaminants that get away do not particularly harm your body, hence if you are looking for a slightly more environment-friendly method for water filtration, this method is ideal.

Colon cancer is the development of carcinogenic cells in the intestine that plays a major role in digestion. Over the years, colon cancer has become a massive threat across the globe. As found by a study, colon cancer remains the third most diagnosed cancer among American adults. Symptoms of Colon Cancer Colon cancer can appear with the benign cells that turn into polyps causing serious damage to health. However, following are the general symptoms that the renowned colon cancer center of the country have found,

• Fatigue
• Irregular bowel movement
• Blood in stool
• Sudden weight loss
• Continuous constipation or diarrhea

Consult a colon doctor If you come across the blood in bowel movements, rush to see a colon doctor. Regular colon screenings can reduce the risk of colon cancer. If you are now 50 years old, start your screening as 25.3% adults aged 75-84 are affected by this cancer in America. The colon cancer doctor can advise you to do certain things including,

• Follow a nutritious diet
• Quit smoking and drinking excessive alcohol
• Exercise regularly to maintain weight

Colon cancer center in the country The colon cancer centers across the country are well-equipped with efficient colon cancer doctors. Have a look at the various centers and their facilities

• Cancer Treatment Centers of America provides targeted therapy, chemotherapy, radiotherapy, surgery and immunotherapy for treating colon cancer.
• Abington Hospital-Jefferson Health focuses on person-centered care approach by undertaking innovative therapies including IMRT and IGRT and performing a laparoscopic colostomy.
• With the excellent surgical team, the Tucker Gosnell Center for Gastrointestinal Cancers undertakes various tools for treating colon cancer including PET/CT, MRI, Intraoperative ultrasound and 3D CT studies.
• The doctors of Albany Medical Center undertake colorectal surgery for colon cancer and other multidisciplinary approaches.

Colon cancer resources include support towards the patients through physically, emotionally and financially. As colon cancer has become a threat to the American society, taking precautions at an early stage is essentially required. Periodically visit the colon cancer doctor to identify the symptoms quickly, and you can acquire the needed resources at the proper time from the center.