Lupus is of many types depending on its nature and the organs it affects. The disease commonly called Lupus is the most virulent form attacking almost all organs. Its medical name is Systemic Lupus erythematosus SLE. Another variety is called discoid lupus which confines it action to the skin only. It does not affect other organs. It results in rashes appearing on the face, scalp and neck. Less than 10% of the patients tend to end up with the systemic variety. There is no means to predict or prevent the progression of this disease. Yet another is drug induced lupus. Two drugs commonly associated with this are, an antihypertensive drug, hydralazine, and the other procainamide used for controlling heart arrhythmia. There are a number of drugs that are known to cause lupus. It is seen that the withdrawal of the concerned drugs brings about the cessation of the disease. A very rare type is called neonatal lupus. This occurs when the mother passes autoimmune antibodies to a fetus. The unborn child and the newborn can have skin rashes and other complications involving heart and blood. Usually a skin rash appears which fades away in about six months. Since 90% of those suffering from lupus are women, estrogen, the female hormone, was thought to have something to do with lupus. A flare up prior to monthly periods and during pregnancy is known to strengthen the thought. However, studies have failed to establish a causal relationship. It is also observed that women who take estrogen as a contraceptive and MHT have not shown any marked increase in developing lupus. Though some group of genes have been found to contribute to the development of lupus no definite genes or group has been identified as causative. No curative treatment is currently available. Nonsteroidal anti-inflammatory (NSAIDs) medicines are used to control inflammation, pain and fever. Stronger NSAIDS are available under prescription. These medicines can have side effects and must only be taken under observation by doctors. An outside prescription use of some antimalarial drugs has been found useful in controlling lupus symptoms. In more difficult cases corticosteroids have been useful to control inflammation of lupus, However, long term use can produce unwanted side effects like weight gain, osteoporosis, hypertension, diabetes. All medication and treatment options should be explored after consultation with a doctor.

Dyson is one of the top brands when it comes to vacuum cleaners. This brand manufactures vacuums of all sizes for households and businesses and they are some of the most powerful cleaning machines that you will ever come across. You will find Dyson Vacuums with both cord and cordless technology. Therefore, buying the right one can get confusing. When buying a vacuum cleaner, you need to keep in mind the amount of cleaning you need to do and the kind of suction power you need. Both of these factors decide the price of the machine. Therefore, before you start shopping, map out your needs clearly. Following are some of the best Dyson vacuums that you must consider.

• Dyson V6 Motorhead This is a top-rated stick vacuum cleaner, which is good for cleaning congested spaces. This cleaner lets you use a stick or a hand vacuum and it makes for some really powerful cleaning with its 20 minutes of powerful suction. It efficiently cleans carpeted areas and hardwood floors while easily reaching corners and under furniture. It is also capable of getting rid of pet hair and cleans dirty stairs fantastically as well.
• Dyson DC65 Animal This is a powerful and bag-less vacuum cleaner that comes with a number of attachments. It is an upright cleaner with a tangle-free turbine. It also offers various brushes for cleaning different surfaces, like stairs, carpets, hardwood, among others. Dyson DC65 is a great machine if you need to clean multiple types of floors (hardwood, tile, carpet) and have pets at home.
• Dyson V6 This is a powerful stick vacuum cleaner that efficiently handles all types of surfaces. You can use it to make your hardwood floors shine while at the same time making your carpets look as good as new. If you have pets and have been looking for a vacuum that will suck and remove all the pet hair from your surfaces, this is the machine you need to bring home. It is also very handy when it comes to cleaning stairs.
• Dyson Ball Multi Floor Upright This upright Dyson vacuum is an easily maneuverable machine. It offers powerful suction along with a cleaner head, which is self-adjusting. This machine is fitted with an instant-release wand, which is ideal for all the nooks and crannies in your house. This model is a great choice for cleaning stairs and it works wonders on hardwood floors as well.

White sauce was originally made served with fettuccine pasta. Known as the Alfredo sauce, White sauce is a hit among those who prefer buttery and cheesy flavor in their pasta. The rich buttery consistency of the white sauce blends well with the spaghetti pasta. It is not too hard to replicate white sauce if you have all the ingredients in place. To prepare white sauce, you will need; one tablespoon olive oil, one tablespoon butter, five garlic cloves, minced, a cup of cooked pasta water, one cup heavy cream, one to two cups of four-cheese Italian White Cheese Blend which may include Mozzarella, White Cheddar, Provolone and Asiago, parsley or chives or green onions, finely chopped for dressing, and a cube of Chicken bouillon. Instructions Heat olive oil and butter on medium flame in a large pan, add minced garlic and cook for about one minute, see to it that it does not burn beyond brown. Reserve some of cooked pasta water. Dissolve one cube of chicken broth bullion in one cup of hot pasta water. Add the cooked pasta water (with the dissolved chicken broth bouillon cube in it) that you had reserved earlier, heavy cream to the pan with cooked garlic. Bring the ingredients to boil, stirring. Once the liquids are boiling, immediately add cheese and keep stirring everything together (the ingredients added earlier and the cream), while boiling until cheese melts. Reduce to simmer and continue to cook, constantly stirring to thicken the sauce for another minute or two. Once boiled down to the desired consistency, add a hint of Italian seasoning herbs and mix well. You can either store the sauce or pour directly on the spaghetti any other pasta that you have cooked. If you are going to use the sauce later, heat it again and then pour on the pasta, else the sauce wont mix well with the pasta. While serving, add finely chopped chives, or green onions, or parsley and sprinkle some oregano on top.  

Top internet service providers are not far behind when it comes to offering Black Friday deals. If you are planning to switch to another internet service provider or upgrade your existing plan, now is the right time. There are quite a few promotions offered to help you save money during the holiday season. Check out the best Black Friday deals on internet services in 2022. AT&T AT&T offers deals twice a year – once in July and the other for Black Friday. Currently, the internet service provider is running promotions for its fiber plans. You can switch to AT&T Fiber for free and get up to a $200 reward card through their online portal. Xfinity Xfinity offers high-speed internet-only gigabit plans starting at $80. Get the best deals by signing up for Xfinity’s 12 or 24-month contract and even through bundle plans. Xfinity offers plans with no term contract. Customers can get unlimited Gig-speed internet for $30 per month plus a free Flex 4K streaming TV box and home Wi-Fi equipment when you add one unlimited mobile line within 90 days. Optimum Optimum is run by the parent company Altice and has great deals every year for Black Friday. Get a $200 or $100 prepaid Visa gift card when you sign up for a qualifying fiber plan - a perfect deal for some extra holiday shopping. Depending on the speed tier, users also get 3 to 12 months of HBO Max subscription. New customers can get Gigabit internet for $50 per month and add on TV services for $30 per month. Verizon With this provider, you can get one of the best internet service deals for mobile LTE or 5G internet, fiber, and DSL. Customers who sign up for Verizon’s Gigabit Connection plan receive a $200 gift card and an 8-piece or 4-piece SimpliSafe security bundle. Additionally, customers can also enjoy free Disney+ for six months or a year and a discount on the Verizon soundbar. Frontier Get a gift card of up to $300, an ultra-fast Wi-Fi 6E system with free activation, and $120 off one year of YouTube TV when you sign up for Frontier’s new plan, Fiber 2 Gig. The plans start at $34.99 per month to $79.99 and include unlimited data. No contract is required to sign up for Frontier’s internet service. CenturyLink CenturyLink offers you a wide variety of deals during major shopping events. Currently, you can save some dollars off your fiber bill as the modem and installation are free with all online orders. The fiber plan costs $65 per month and includes unlimited internet. CenturyLink’s DSL plan costs $50 per month and is capped at 1 TB per month. Cox Cox offers affordable prepaid plans, cable, and fiber connections. Sign up for a 12-month contract to get the lowest prices. Its fastest plan is the Gigablast, priced at $79.99 per month. However, this offer ends soon so be on the lookout for better ones. There are also plans as low as $49.99 with no annual contract requirement. HughesNet HughesNet is a satellite internet provider offering services virtually across the country. Last year, the internet service provider offered a $100 prepaid card, free installation, and built-in home Wi-Fi with no hard data caps to new customers. During the Black Friday sale, HughesNet offers incentives to new customers. Windstream Enjoy high-speed internet at just $66 when you sign up for Windstream’s gigabit internet. Bundle plans with TV and internet start at $55. A limited-time promotional offer for new customers is that they will receive a $100 online credit on their first month’s bill. Also, when you sign up for Kinetic Internet you will get to enjoy three months of Gig speed internet. Spectrum Spectrum’s cable internet plans offer unlimited data and do not require any contract for its service. New customers can save $25 on their monthly bill for 12 months. On select internet and TV plans, Spectrum is offering free Peacock Premium for up to 12 months. The above deals are subject to change, so be sure to keep a check on all the deals during the Black Friday sale.

Asthma inhalers are classified into different types depending on the mechanisms of their working. The various types include pressurized metered dose inhalers, breath actuated inhalers, inhalers with spacer devices and nebulizers. Each of these have their own merits and demerits. Pressurized metered dose inhalers or SMDI: This type of inhaler was very popular and was unchallenged for about 40 years. Its biggest advantage is its simple operation. It can be used with almost all medicines. It consists of a pressured, inactive, carrier gas that propels the medicine in each puff when the piston is depressed. It is an L-shaped equipment with the longer arm containing the carrier gas and the shorter arm the mouthpiece. The common factors that made this inhaler less popular are listed below.

• The inhaler should always be well shaken before use.
• Inhalation and pressing the cylinder were not synchronized.
• The breath could not be held for long enough after the puff was taken in.

Breath-activated inhalers: Some of them are still MDIs but pressing of the canister is eliminated. One inhales hard at the mouth piece to get the medicine powder released and into the lungs. One needs to breathe in fairly hard to get all the medicine released and into the lung. This is its important drawback as many may not have the suction power required, and they are somewhat bigger, while the advantage is that it requires little or no coordination. Inhalers with spacer devices: It consists of the pressurized carrier gas cylinder like the SMDI. It has a spindle like attachment at the mouthpiece of which a face mask can be attached for the use of babies and the really old and fragile patients. The medicine, on release, is held in the spacer which is a reservoir. The mask has a valve which opens and closes with the breathing. One has to breathe till the medicine is completely used up before pressing the piston again if more than one puff is recommended. There are several brands in this type. Usual guidelines of SMDIs hold good for this type too. The spacer needs to be cleaned as per manufacturer's instructions. Nebulizers: Nebulizers are machines that turn the liquid bronchodilators into a mist and this is to be breathed. These are used in hospitals for severe attacks of asthma and needs large quantities of medicine. It is also useful for frail patients who have weak breathing.

Gold metal detectors are made to detect and identify if there is gold underneath the surface. Gold metal detectors can sometimes be strong enough to detect gold from a substantial depth. They help in identifying any precious gold underground. Since gold nuggets are very small in size, they are very hard to find. Using the best gold detectors is the only way to find the gold. Using substandard gold detectors can let you miss out on some pieces of gold. Further, not just any metal detector can be used to find gold. This is because gold can only be found in highly mineralized soil. Any soil containing more than one metal can create problems for your hunt for gold. Hence, it is required that for finding gold, only a gold metal detector be used, and one that is good. Some of the best gold metal detectors can be expensive, but very effective. The gold you find with these metal detectors can easily make you forget their costs. There are many brands and companies that produce gold metal detectors. Here are five best gold metal detectors in the market right now: Fisher® Gold Bug Pro It is a very user-friendly machine which can be easily picked up by a first-time user. This detector is lightweight and can be used in shallow grounds. This is helpful as it increases your search time without tiring you. White’s GoldMaster GMT Metal Detector This is one of the oldest detectors in the market and also one of the most efficient. The GMT is extremely sensitive and can pick up traces of gold better than most contemporary gold detectors. This is perfect for complex grounds as it adjusts itself to the varied conditions of the ground. Fisher® Gold Bug 2 This is also one of the oldest products in the market and has not failed to deliver. It is very sensitive and catches on to very small nuggets of gold as well. It can detect gold that is as small as a pinhead and can detect larger pieces of gold as well, besides how far deep the gold follows through. Garrett ATX Metal Detector This gold metal detector uses pulse induction detection which provides a larger range than other gold detectors. It is resistant to water like most good detectors but is resistant to up to 10 feet of water. It is waterproof, which minimizes the damage while being outdoors.